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MDR vs IVDR: which regime is your product in?

Medical devices and in-vitro diagnostics run on two different EU regulations, with different risk classes and different routes to a CE mark. Knowing which one you're in — and your exact class — is the first decision, because it determines everything downstream.

9 min read Reviewed by Ralf Müller, Market Access & Regulatory Lead Updated 2026
In one paragraph

If your product acts on or in the body, it's a medical device under MDR (EU 2017/745), classified I / IIa / IIb / III. If it examines samples taken from the body — blood, tissue, DNA — it's an in-vitro diagnostic under IVDR (EU 2017/746), classified A / B / C / D. The two regimes share a CE-marking logic but differ on classification, evidence and — critically — when a Notified Body must be involved. The IVDR reclassification, in particular, pulled most diagnostics into Notified-Body routes for the first time.

Two regimes, one first question

Before route, evidence, timeline or cost, one question sets the whole path: which regulation governs your product, and at what class?

MDR and IVDR are not interchangeable. They cover different products, use different classification systems, and demand different clinical or performance evidence. Get the regime or the class wrong and the entire conformity plan is built on the wrong foundation — a mistake that surfaces late and costs time you can't recover.

Your regime and class isn't paperwork. It's the decision every other decision hangs from.

Side by side

Two regulations, two class systems

The green cells are the classes that require a Notified Body (Benannte Stelle) conformity assessment. The pale cells can be self-declared.

Devices

MDR

Regulation (EU) 2017/745 · medical devices
CoversProducts that act on or in the body — instruments, implants, software as a device, equipment.
ClassesRisk-based, four levels.
Iself
IIaNB
IIbNB
IIINB
Class I self-declared — except sterile / measuring / reusable-surgical aspects, which need a Notified Body.
Diagnostics

IVDR

Regulation (EU) 2017/746 · in-vitro diagnostics
CoversTests performed on samples taken from the body — lab assays, point-of-care, companion diagnostics, software.
ClassesRisk to individual + public health, four levels.
Aself*
BNB
CNB
DNB
Only class A (non-sterile) self-declared. B, C and D need a Notified Body — the change that caught the industry.

Same CE-marking philosophy, different mechanics — and a very different share of products that now need external assessment. We keep devices and diagnostics on separate tracks for exactly this reason.

How classification works

Both regimes classify by rules, not by product name. You apply the classification rules in the regulation's annex to your device's intended purpose, duration of use, invasiveness and the risk it carries.

  • MDR — classes I, IIa, IIb, III, rising with risk. Duration (transient / short / long-term), invasiveness, whether it's active, and where it acts all feed the rule.
  • IVDR — classes A (low), B, C, D (high), driven by the risk to the individual patient and to public health. A test that could cause a wrong life-or-death decision, or miss a transmissible-disease screen, sits high.

The intended purpose you write is decisive: a small wording change can move a product up or down a class, and with it the whole evidence and Notified-Body burden.

What both regimes require

Whichever regulation applies, the same building blocks recur — and for a non-EU manufacturer, several must be set up locally before a product can be placed on the EU market.

CE markingTechnical documentationClinical / performance evaluationAuthorised Representative (EC REP)PRRC (Art 15)UDIEUDAMEDPost-market surveillanceVigilance reporting

Two are easy to underestimate: the Authorised Representative (EC REP) that a non-EU manufacturer must appoint in the EU, and the Person Responsible for Regulatory Compliance (PRRC) the manufacturer must have available. Both are named, accountable roles — not documents.

Why it decides everything downstream

Your regime and class set the conformity route, the evidence you must generate, the timeline and the cost — and they shape what comes after the CE mark, too. Because a CE mark still isn't reimbursement: how a device or diagnostic gets paid for in Germany runs on a separate system entirely.

Regime and class get you the CE mark. Reimbursement is the next, separate project.

RM
Reviewed by Ralf Müller
Market Access & Regulatory Lead · 15 years in German pharma & medtech
Bringing a device or diagnostic to Germany?

We confirm your regime and class — then the route to paid.

In a focused session we pin down MDR vs IVDR and your exact class, the realistic CE timeline (Notified-Body bottleneck included), and the reimbursement route that fits — so authorization and market access aren't two disconnected projects.